• Neuroscience

• Alzheimer's Disease and Anesthetics

• Central Cholinergic System and Anesthesia 

• Post-operative cognitive dysfunction (POCD)

• Neuroprotection

• Neuromuscular blocking drugs  

• Opioids  

• Brain monitoring in Anesthesia and Intensive Care

Certificated European Society of Regional Anestesia (ESRA)

Journal Reviewer "Critical Care Medicine"

Guest Reviewer "British Journal Anaesthesia"

Guest Reviewer "Clinical Chemistry and Laboratory Medicine"

Guest Reviewer "Acta Anaesthesiologica Scandinavica"

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Grasso G, Meli F, Fodale V, Calapai G, Buemi M, Iacopino DG.
 Neuroprotective potential of erythropoietin and darbepoetin alfa in an
experimental model of sciatic nerve injury. Laboratory investigation.
J Neurosurg Spine. 2007 Dec;7(6):645-51.

Fodale V, Romeo M, Mafrica F.
 Fentanyl are we paying too high a price?
J Opioid Manag. 2007 May-Jun;3(3):123-6.

Grasso G, Sfacteria A, Meli F, Fodale V, Buemi M, Iacopino DG.
 Neuroprotection by erythropoietin administration after experimental traumatic brain injury.
Brain Res. 2007 Nov 28;1182:99-105.

Grasso G, Sfacteria A, Meli F, Passalacqua M, Fodale V, Buemi M, Giambartino
F, Iacopino DG, Tomasello F.
 The role of erythropoietin in neuroprotection: therapeutic perspectives.
Drug News Perspect. 2007 Jun;20:315-20.

Collyer TC, Frater R, Fodale V.

Alzheimer's Disease and Anaesthesia

Br. J. Anaesth. 2007 May; 98: 692-694.

Santamaria LB, Di Paola C, Mafrica F, Fodale V.
 Preanesthetic evaluation and assessment of children with Down's syndrome.
ScientificWorldJournal. 2007 Feb 19;7:242-51.

Fodale V, Di Pietro R, Santamaria S.
 Viagra, surgery and anesthesia: a dangerous cocktail with a risk of blindness.
Med Hypotheses. 2007;68(4):880-2.

Mafrica F, Fodale V.
 Opioids and Down's syndrome.
J Opioid Manag. 2006 Mar-Apr;2(2):93-8.

Fodale V, Mafrica F, Santamaria LB.
 Killer fentanyl: a lesson from anaesthesiology.
Lancet. 2006 Oct 7;368(9543):1237-8.

3:  Fodale V, Quattrone D, Trecroci C, Caminiti V, Santamaria LB.
 Alzheimer's disease and anaesthesia: implications for the central cholinergic
system.
Br J Anaesth. 2006 Oct;97(4):445-52.

Fodale V, Mafrica F, Caminiti V, Grasso G.
 The cholinergic system in Down's syndrome.
J Intellect Disabil. 2006 Sep;10(3):261-74.

Fodale V, Di Pietro R, Ferreri F, Tescione M, Russo G, Santamaria S, Pratico
C.
 The effect of peribulbar block with ropivacaine on bi-hemispheric cerebral
oxygen saturation in aged patients.
Anaesthesia. 2006 Aug;61(8):764-7.

Conti A, Iacopino DG, Fodale V, Micalizzi S, Penna O, Santamaria LB.
 Cerebral haemodynamic changes during propofol-remifentanil or sevoflurane
anaesthesia: transcranial Doppler study under bispectral index monitoring.
Br J Anaesth. 2006 Sep;97(3):333-9.

Fodale V, Pratico C, Tescione M, Tanania S, Lucanto T, Santamaria LB.
 Evidence of acute tolerance to remifentanil in intensive care but not in
anesthesia.
J Clin Anesth. 2006 Jun;18(4):293-6.

Fodale V, Tescione M, Roscitano C, Pino G, Amato A, Santamaria LB.
 Effect of tramadol on Bispectral Index during intravenous anaesthesia with
propofol and remifentanil.
Anaesth Intensive Care. 2006 Feb;34(1):36-9.

Mafrica F, Schifilliti D, Fodale V.
 Pain in Down's syndrome.
ScientificWorldJournal. 2006 Jan 26;6:140-7.

Fodale V, Pratico C, Signer MR, Santamaria LB.
 Perinatal neuroprotection by muscle relaxants against hypoxic-ischemic lesions: is it a possible hypothesis?
J Matern Fetal Neonatal Med. 2005 Aug;18(2):133-6.

Pratico C, Quattrone D, Lucanto T, Amato A, Penna O, Roscitano C, Fodale V.
 Drugs of anesthesia acting on central cholinergic system may cause
post-operative cognitive dysfunction and delirium.
Med Hypotheses. 2005;65(5):972-82.

Fodale V, Mazzeo A, Pratico C, Aguennouz M, Toscano A, Santamaria LB, Vita
G.
 Fatal exacerbation of peripheral neuropathy during lamivudine therapy: evidence
for iatrogenic mitochondrial damage.
Anaesthesia. 2005 Aug;60(8):806-10.

Fodale V, Pratico C, Tescione M, Lucanto T, Tanania S, Santamaria LB.
 Comparative cost-analysis of a propofol-cisatracurium-based anesthesia with
remifentanil or fentanyl for laparoscopic surgery.
Surg Laparosc Endosc Percutan Tech. 2005 Jun;15(3):149-52.

Fodale V, Pratico C, Tescione M, Tanania S, Lucanto T, Santamaria LB.
 Tramadol does not modify the Bispectral Index during anaesthesia with
sevoflurane and remifentanil.
Br J Anaesth. 2005 Aug;95(2):212-5.

Fodale V, Pratico C, Lucanto T, Mazzeo AT, Pino G, Santamaria LB.
 Complete recovery from prolonged cardiac arrest following self-administration
of cisatracurium.
Eur J Anaesthesiol. 2005 Jan;22(1):73-5.

Fodale V, Santamaria LB.
 In clinical practice, coadministration of sevoflurane or propofol could
antagonize remifentanil stimulation of N-methyl-D-aspartate receptors.
Anesthesiology. 2005 Mar;102(3):695-6;

Fodale V, Mondello B, Mirenda F, Spinelli F, Santamaria LB.
 Tramadol and vocal cord closure.
Anesthesiology. 2005 Jan;102(1):227-9.

Fodale V, Pratico C.
 Bispectral Index monitoring for assessment of level of consciousness in
brain-injured patients: the journey continues.
Crit Care Med. 2004 Dec;32(12):2545-6.

Fodale V, Tescione M, Pratico C.
 Cholinesterase inhibitors, neuromuscular blocking drugs and perioperative
memory enhancement.
Anesthesiology. 2004 Dec;101(6):1483-4.

Barbuscia M, Gorgone S, Di Pietro N, Rizzo AG, Melita G, Fodale V, Sano M,
De Luca M, Marando A, Pratico C.
 [Ileum-colon junction benign obstructions]
G Chir. 2004 Jun-Jul;25(6-7):251-8.

Fodale V, Pratico C, Santamaria LB.
 Coadministration of propofol and midazolam decreases bispectral index value as
a result of synergic muscle relaxant action on the motor system.
Anesthesiology. 2004 Sep;101(3):799;

Fodale V, Pratico C, Leto G, Caminiti V, Mazzeo AT, Lucanto T.
 Propofol relieves post-extubation laryngospasm in obstetric anesthesia.
Int J Obstet Anesth. 2004 Jul;13(3):196-7.

Fodale V, Santamaria LB.
 Different actions of sevoflurane and propofol on central nicotinic receptors
may explain differences in hypnotic antagonism by cholinesterase inhibitors.
Br J Anaesth. 2004 May;92(5):773-4;

Fodale V, Pratico C, Santamaria LB.
 Potential neuroprotective properties of atracurium and cisatracurium in
neurosurgical anaesthesia.
Eur J Anaesthesiol. 2004 Apr;21(4):333-4;

Fodale V, Santamaria LB.
 Is overestimation of bispectral index in sedated intensive care unit patients
only related to electromyographic activity?
Anesthesiology. 2004 Mar;100(3):746; author reply 746-7.

Fodale V, Pratico C, Santamaria LB.
 Drugs of anesthesia, central nicotinic receptors and Parkinson's disease.
Parkinsonism Relat Disord. 2004 Mar;10(3):189-90.

Fodale V, Pratico C, Girlanda P, Baradello A, Lucanto T, Rodolico C,
Nicolosi C, Rovere V, Santamaria LB, Dattola R.
 Acute motor axonal polyneuropathy after a cisatracurium infusion and
concomitant corticosteroid therapy.
Br J Anaesth. 2004 Feb;92(2):289-93.

Fodale V, Pratico' C, Piana F, Caruso A, Lucanto T, Coniglio S, Santamaria
LB.
 Propofol and remifentanil without muscle relaxants in a patient with myasthenia gravis for emergency surgery.
Can J Anaesth. 2003 Dec;50(10):1083-4.

Fodale V, Santamaria LB.
 The inhibition of central nicotinic nAch receptors is the possible cause of
prolonged cognitive impairment after anesthesia.
Anesth Analg. 2003 Oct;97(4):1207

Fodale V, Santamaria LB.
 Drugs of anesthesia, central nicotinic receptors and post-operative cognitive
dysfunction.
Acta Anaesthesiol Scand. 2003 Oct;47(9):1180;

 Barbuscia M, Pratico C, Rizzo AG, Puliatti F, Melita G, Fodale V, Mazzeo
AT, Gorgone S.
 [Treatment of substernal goiter. Our experience]
G Chir. 2003 May;24(5):193-7.

Fodale V, Santamaria LB.
 The possible neuroprotective effect of laudanosine, an atracurium and
cisatracurium metabolite.
Acta Anaesthesiol Scand. 2003 Jul;47(6):780; 780-1.

Fodale V, Santamaria LB.
 Laudanosine, an atracurium and cisatracurium metabolite.
Eur J Anaesthesiol. 2002 Jul;19(7):466-73.

Santamaria LB, Fodale V, Mazzola T.
 [Systemic complications of local anesthetics]
Minerva Anestesiol. 1992 Oct;58(10):1071-8.

Santamaria LB, Fodale V, Mandolfino T, Lucanto T, de Lieto Vollaro I,
Ballistreri I, Spavara M.
 [Transdermal scopolamine reduces nausea, vomiting and sialorrhea in the
postoperative period in teeth and mouth surgery]
Minerva Anestesiol. 1991 Sep;57(9):686-7.

Pratico C, Santamaria LB, Fodale V, Lucanto T, Oliva R, Franco G, Amato A.
 [The use of propofol in tracheal intubation in the surgery of traumatic lesions
of the face]
Minerva Anestesiol. 1991 Sep;57(9):604-5.

Santamaria LB, Pratico C, Venuti FS, Lucanto T, David A, Fodale V,
Trimarchi G.
 [Sedation with propofol in COPD patients in the ICU]
Minerva Anestesiol. 1991 Jul-Aug;57(7-8):417-22.

Pratico C, Pedulla E, Fodale V, David A, Lucanto T, Franco G, Sinardi AU.
 [A singular case of Blizzard syndrome diagnosed at the ICU]
Minerva Anestesiol. 1990 Oct;56(10):1359-60.

Gambardella G, Santamaria LB, Toscano SG, Staropoli C, Fodale V, Montanini
S, Tomasello F.
 Brain metastases: surgical versus conservative treatment.
J Neurosurg Sci. 1990 Jul-Dec;34(3-4):309-14.

Di Giorgio RM, Fodale V, Macaione S, De Luca GC.
 Effects of thyroxine on methionine adenosyltransferase activity in rat cerebral
cortex and cerebellum during postnatal development.
J Neurochem. 1983 Sep;41(3):607-10.