Vincenzo Fodale, MD

Aggregated Professor Anesthesiology and Intensive Care

Department of Neurosciences, Psychiatric and Anesthesiological Sciences.

University of Messina  

Messina, Italy

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Contact Information  
University of Messina.  
Section of Anesthesiology and Intensive Care Unit.
University Hospital "G.Martino"
Via C.Valeria
98125 Messina, Italy

 

E-Mail Address: vfodale@unime.it

PERSONAL WEB SITE: www.fodale.com   www.fodale.it

UNIVERSITY PERSONAL WEB PAGE:

http://poli.unime.it/medicina/personale/visualizza_doc.php?id=598&tabepoli=doc_

 

Education

Medical School

University of Messina, School of Medicine (M.D. 1986)  

Residencies and Fellowships

University of Messina,  Hospitals and Clinics.

Current Research Interests
  • Neuroscience

  • Alzheimer's Disease and Anesthetics

  • Central Cholinergic System and Anesthesia 

  • Post-operative cognitive dysfunction (POCD)

  • Neuroprotection

  • Neuromuscular blocking drugs  

  • Opioids  

  • Brain monitoring in Anesthesia and Intensive Care

Additional

Certificated European Society of Regional Anestesia (ESRA)

Editorial Board "Journal Alzheimer's Disease" (2008)

Journal Reviewer "Critical Care Medicine"

Guest Reviewer "British Journal Anaesthesia"

Guest Reviewer "Clinical Chemistry and Laboratory Medicine"

Guest Reviewer "Acta Anaesthesiologica Scandinavica"

 

Main Publications
  

 

    Click to search for citations by this author.

 
  Mandal PK, Schifilliti D, Mafrica F, Fodale V.Inhaled anesthesia and
cognitive performance.Drugs Today (Barc). 2009 Jan;45(1):47-54.

 
     
  Mandal PK, Fodale V. Isoflurane and desflurane at clinically relevant
concentrations induce amyloid beta-peptide oligomerization: an NMR study. Biochem Biophys Res Commun. 2009 Feb 13;379(3):716-20.
 
     
  Fodale V, Mondello S, Aloisi C, Schifilliti D, Santamaria L. Genotoxic effects
of anesthetic agents. Expert Opin Drug Saf. 2008 Jul;7(4):447-58.

 

     
  Mafrica F, Fodale V. Thyroid function, Alzheimer's disease and postoperative
cognitive dysfunction: a tale of dangerous liaisons?. J Alzheimers Dis. 2008
May;14(1):95-105.

 

     
  Fodale V, Mafrica F, Santamaria LB, Coleman JJ. Killer fentanyl: is the fear
justified?. Expert Opin Drug Saf. 2008 May;7(3):213-7.

 

     
  Fodale V, La Monaca E. Propofol infusion syndrome: an overview of a perplexing
disease. Drug Saf. 2008;31(4):293-303.

 

     
  Fodale V, Schifilliti D, Praticò C, Santamaria LB. Remifentanil and the
brain. Acta Anaesthesiol Scand. 2008 Mar;52(3):319-26.

 

     
  Mondello S, Fodale V, Cannavò S, Aloisi C, Almoto B, Buemi M, Santamaria LB.
Hypophosphatemia as unusual cause of ARDS in Cushing's syndrome secondary to ectopic CRH production. A case report. ScientificWorldJournal. 2008 Feb
6;8:138-44.

 

     
  Fodale V, Santamaria LB, Grasso G. Neuroprotective properties of xenon and
helium in an in vitro model of traumatic brain injury: one small step or one big
jump?. Crit Care Med. 2008 Feb;36(2):647-8.

 

     
  Fodale V, Santamaria LB. Cholinesterase inhibitors improve survival in
experimental sepsis: a new way to activate the cholinergic anti-inflammatory
pathway. Crit Care Med. 2008 Feb;36(2):622-3.

 

     
 
Grasso G, Sfacteria A, Meli F, Passalacqua M, Fodale V, Buemi M, Giambartino
F, Iacopino DG, Tomasello F. The role of erythropoietin in neuroprotection:
therapeutic perspectives. Drug News Perspect. 2007 Jun;20(5):315-20.

 

     

Grasso G, Meli F, Fodale V, Calapai G, Buemi M, Iacopino DG.
 Neuroprotective potential of erythropoietin and darbepoetin alfa in an
experimental model of sciatic nerve injury. Laboratory investigation.
J Neurosurg Spine. 2007 Dec;7(6):645-51.

 

     

Fodale V, Romeo M, Mafrica F.
 Fentanyl are we paying too high a price?
J Opioid Manag. 2007 May-Jun;3(3):123-6.

 

     

Grasso G, Sfacteria A, Meli F, Fodale V, Buemi M, Iacopino DG.
 Neuroprotection by erythropoietin administration after experimental traumatic brain injury.
Brain Res. 2007 Nov 28;1182:99-105.

 

     

Grasso G, Sfacteria A, Meli F, Passalacqua M, Fodale V, Buemi M, Giambartino
F, Iacopino DG, Tomasello F.
 The role of erythropoietin in neuroprotection: therapeutic perspectives.
Drug News Perspect. 2007 Jun;20:315-20.

 

     
 

 

Abstract

 

Collyer TC, Frater R, Fodale V.

Alzheimer's Disease and Anaesthesia

Br. J. Anaesth. 2007 May; 98: 692-694.

 

Abstract

   

Santamaria LB, Di Paola C, Mafrica F, Fodale V.
 Preanesthetic evaluation and assessment of children with Down's syndrome.
ScientificWorldJournal. 2007 Feb 19;7:242-51.

Abstract    
 

 

Abstract    

Fodale V, Di Pietro R, Santamaria S.
 Viagra, surgery and anesthesia: a dangerous cocktail with a risk of blindness.
Med Hypotheses. 2007;68(4):880-2.

Abstract

   

Mafrica F, Fodale V.
 Opioids and Down's syndrome.
J Opioid Manag. 2006 Mar-Apr;2(2):93-8.

     

Fodale V, Mafrica F, Santamaria LB.
 Killer fentanyl: a lesson from anaesthesiology.
Lancet. 2006 Oct 7;368(9543):1237-8.

Abstract

3:  Fodale V, Quattrone D, Trecroci C, Caminiti V, Santamaria LB.
 Alzheimer's disease and anaesthesia: implications for the central cholinergic
system.
Br J Anaesth. 2006 Oct;97(4):445-52.

Abstract

Fodale V, Mafrica F, Caminiti V, Grasso G.
 The cholinergic system in Down's syndrome.
J Intellect Disabil. 2006 Sep;10(3):261-74.

Abstract

Fodale V, Di Pietro R, Ferreri F, Tescione M, Russo G, Santamaria S, Pratico
C.
 The effect of peribulbar block with ropivacaine on bi-hemispheric cerebral
oxygen saturation in aged patients.
Anaesthesia. 2006 Aug;61(8):764-7.

Abstract

Conti A, Iacopino DG, Fodale V, Micalizzi S, Penna O, Santamaria LB.
 Cerebral haemodynamic changes during propofol-remifentanil or sevoflurane
anaesthesia: transcranial Doppler study under bispectral index monitoring.
Br J Anaesth. 2006 Sep;97(3):333-9.

Abstract

Fodale V, Pratico C, Tescione M, Tanania S, Lucanto T, Santamaria LB.
 Evidence of acute tolerance to remifentanil in intensive care but not in
anesthesia.
J Clin Anesth. 2006 Jun;18(4):293-6.

Abstract

Fodale V, Tescione M, Roscitano C, Pino G, Amato A, Santamaria LB.
 Effect of tramadol on Bispectral Index during intravenous anaesthesia with
propofol and remifentanil.
Anaesth Intensive Care. 2006 Feb;34(1):36-9.

Abstract

Mafrica F, Schifilliti D, Fodale V.
 Pain in Down's syndrome.
ScientificWorldJournal. 2006 Jan 26;6:140-7.

Abstract

Fodale V, Pratico C, Signer MR, Santamaria LB.
 Perinatal neuroprotection by muscle relaxants against hypoxic-ischemic lesions: is it a possible hypothesis?
J Matern Fetal Neonatal Med. 2005 Aug;18(2):133-6.

Abstract

Pratico C, Quattrone D, Lucanto T, Amato A, Penna O, Roscitano C, Fodale V.
 Drugs of anesthesia acting on central cholinergic system may cause
post-operative cognitive dysfunction and delirium.
Med Hypotheses. 2005;65(5):972-82.

Abstract    

Fodale V, Mazzeo A, Pratico C, Aguennouz M, Toscano A, Santamaria LB, Vita
G.
 Fatal exacerbation of peripheral neuropathy during lamivudine therapy: evidence
for iatrogenic mitochondrial damage.
Anaesthesia. 2005 Aug;60(8):806-10.

Abstract    

Fodale V, Pratico C, Tescione M, Lucanto T, Tanania S, Santamaria LB.
 Comparative cost-analysis of a propofol-cisatracurium-based anesthesia with
remifentanil or fentanyl for laparoscopic surgery.
Surg Laparosc Endosc Percutan Tech. 2005 Jun;15(3):149-52.

Abstract    

Fodale V, Pratico C, Tescione M, Tanania S, Lucanto T, Santamaria LB.
 Tramadol does not modify the Bispectral Index during anaesthesia with
sevoflurane and remifentanil.
Br J Anaesth. 2005 Aug;95(2):212-5.

Abstract    

Fodale V, Pratico C, Lucanto T, Mazzeo AT, Pino G, Santamaria LB.
 Complete recovery from prolonged cardiac arrest following self-administration
of cisatracurium.
Eur J Anaesthesiol. 2005 Jan;22(1):73-5.

Abstract    

Fodale V, Santamaria LB.
 In clinical practice, coadministration of sevoflurane or propofol could
antagonize remifentanil stimulation of N-methyl-D-aspartate receptors.
Anesthesiology. 2005 Mar;102(3):695-6;

Abstract    

Fodale V, Mondello B, Mirenda F, Spinelli F, Santamaria LB.
 Tramadol and vocal cord closure.
Anesthesiology. 2005 Jan;102(1):227-9.

Abstract    

Fodale V, Pratico C.
 Bispectral Index monitoring for assessment of level of consciousness in
brain-injured patients: the journey continues.
Crit Care Med. 2004 Dec;32(12):2545-6.

Abstract    

Fodale V, Tescione M, Pratico C.
 Cholinesterase inhibitors, neuromuscular blocking drugs and perioperative
memory enhancement.
Anesthesiology. 2004 Dec;101(6):1483-4.

Abstract    
 

Barbuscia M, Gorgone S, Di Pietro N, Rizzo AG, Melita G, Fodale V, Sano M,
De Luca M, Marando A, Pratico C.
 [Ileum-colon junction benign obstructions]
G Chir. 2004 Jun-Jul;25(6-7):251-8.

Abstract    

Fodale V, Pratico C, Santamaria LB.
 Coadministration of propofol and midazolam decreases bispectral index value as
a result of synergic muscle relaxant action on the motor system.
Anesthesiology. 2004 Sep;101(3):799;

Abstract    

Fodale V, Pratico C, Leto G, Caminiti V, Mazzeo AT, Lucanto T.
 Propofol relieves post-extubation laryngospasm in obstetric anesthesia.
Int J Obstet Anesth. 2004 Jul;13(3):196-7.

Abstract    

Fodale V, Santamaria LB.
 Different actions of sevoflurane and propofol on central nicotinic receptors
may explain differences in hypnotic antagonism by cholinesterase inhibitors.
Br J Anaesth. 2004 May;92(5):773-4;

Abstract    

Fodale V, Pratico C, Santamaria LB.
 Potential neuroprotective properties of atracurium and cisatracurium in
neurosurgical anaesthesia.
Eur J Anaesthesiol. 2004 Apr;21(4):333-4;

Abstract    

Fodale V, Santamaria LB.
 Is overestimation of bispectral index in sedated intensive care unit patients
only related to electromyographic activity?
Anesthesiology. 2004 Mar;100(3):746; author reply 746-7.

Abstract    

Fodale V, Pratico C, Santamaria LB.
 Drugs of anesthesia, central nicotinic receptors and Parkinson's disease.
Parkinsonism Relat Disord. 2004 Mar;10(3):189-90.

Abstract    

Fodale V, Pratico C, Girlanda P, Baradello A, Lucanto T, Rodolico C,
Nicolosi C, Rovere V, Santamaria LB, Dattola R.
 Acute motor axonal polyneuropathy after a cisatracurium infusion and
concomitant corticosteroid therapy.
Br J Anaesth. 2004 Feb;92(2):289-93.

Abstract    

Fodale V, Pratico' C, Piana F, Caruso A, Lucanto T, Coniglio S, Santamaria
LB.
 Propofol and remifentanil without muscle relaxants in a patient with myasthenia gravis for emergency surgery.
Can J Anaesth. 2003 Dec;50(10):1083-4.

Abstract    

Fodale V, Santamaria LB.
 The inhibition of central nicotinic nAch receptors is the possible cause of
prolonged cognitive impairment after anesthesia.
Anesth Analg. 2003 Oct;97(4):1207

Abstract    

Fodale V, Santamaria LB.
 Drugs of anesthesia, central nicotinic receptors and post-operative cognitive
dysfunction.
Acta Anaesthesiol Scand. 2003 Oct;47(9):1180;

Abstract    
 

 Barbuscia M, Pratico C, Rizzo AG, Puliatti F, Melita G, Fodale V, Mazzeo
AT, Gorgone S.
 [Treatment of substernal goiter. Our experience]
G Chir. 2003 May;24(5):193-7.

Abstract    

Fodale V, Santamaria LB.
 The possible neuroprotective effect of laudanosine, an atracurium and
cisatracurium metabolite.
Acta Anaesthesiol Scand. 2003 Jul;47(6):780; 780-1.

Abstract    

Fodale V, Santamaria LB.
 Laudanosine, an atracurium and cisatracurium metabolite.
Eur J Anaesthesiol. 2002 Jul;19(7):466-73.

Abstract    
 

Santamaria LB, Fodale V, Mazzola T.
 [Systemic complications of local anesthetics]
Minerva Anestesiol. 1992 Oct;58(10):1071-8.

     
 

Santamaria LB, Fodale V, Mandolfino T, Lucanto T, de Lieto Vollaro I,
Ballistreri I, Spavara M.
 [Transdermal scopolamine reduces nausea, vomiting and sialorrhea in the
postoperative period in teeth and mouth surgery]
Minerva Anestesiol. 1991 Sep;57(9):686-7.

     
 

Pratico C, Santamaria LB, Fodale V, Lucanto T, Oliva R, Franco G, Amato A.
 [The use of propofol in tracheal intubation in the surgery of traumatic lesions
of the face]
Minerva Anestesiol. 1991 Sep;57(9):604-5.

     
 

Santamaria LB, Pratico C, Venuti FS, Lucanto T, David A, Fodale V,
Trimarchi G.
 [Sedation with propofol in COPD patients in the ICU]
Minerva Anestesiol. 1991 Jul-Aug;57(7-8):417-22.

     
 

Pratico C, Pedulla E, Fodale V, David A, Lucanto T, Franco G, Sinardi AU.
 [A singular case of Blizzard syndrome diagnosed at the ICU]
Minerva Anestesiol. 1990 Oct;56(10):1359-60.

     
 

Gambardella G, Santamaria LB, Toscano SG, Staropoli C, Fodale V, Montanini
S, Tomasello F.
 Brain metastases: surgical versus conservative treatment.
J Neurosurg Sci. 1990 Jul-Dec;34(3-4):309-14.

     
 

Di Giorgio RM, Fodale V, Macaione S, De Luca GC.
 Effects of thyroxine on methionine adenosyltransferase activity in rat cerebral
cortex and cerebellum during postnatal development.
J Neurochem. 1983 Sep;41(3):607-10.